Peptide Vials
CJC-1295 NO DAC Vial
CJC-1295 No DAC, clearly named. Modified GRF 1-29, a 29-residue GHRH analog with four stabilising substitutions, in 5 mg and 10 mg lyophilized vials.
Certificate of analysis View available reports and lot details
CJC 1295 No Dac 10 mg
Product identification & intended use
SKU:
For laboratory research use only. Not for human or veterinary use.
Description
CJC-1295 No DAC, more precisely Modified GRF 1-29, is a 29-amino-acid analog of growth hormone-releasing hormone. Four amino-acid changes make it far more resistant to enzymes than sermorelin. We supply it in 5 mg and 10 mg lyophilized vials.
Chemical identity & storage
| Compound / component | CAS number | Molecular weight | Specification status |
|---|---|---|---|
| CJC-1295 No DAC | 863288-34-0 | 3367.9 g/mol Formula: C152H252N44O42 |
Catalog reference specification |
Storage: Keep sealed lyophilized material cold and protected from light. For long-term storage, keep at -20°C or below. After reconstitution, store at 2–8°C and avoid repeated freeze–thaw cycles.
What CJC-1295 No DAC is.
The name is the confusing part. ConjuChem’s original CJC-1295 carried a Drug Affinity Complex (DAC), a reactive linker that attaches the peptide to albumin in the blood and stretches its half-life to days.
Take the linker away and you have No DAC. It acts for a much shorter time, nearer to natural GHRH pulses. Its four substitutions, D-Ala2, Gln8, Ala15 and Leu27, guard it against DPP-4 cleavage and oxidation.
At a glance.
| Sequence | Y-(D-Ala)-DAIFTQSYRKVLAQLSARKLLQDILSR-NH2 |
|---|---|
| Length | 29 amino acids, C-terminal amide |
| Changes from sermorelin | D-Ala2, Gln8, Ala15, Leu27 |
| Molecular formula | C152H252N44O42 |
| Molecular weight | ≈ 3368 g/mol |
| Also known as | Mod GRF 1-29, modified GRF (1-29), tetrasubstituted GRF |
| Form | Lyophilized powder |
| Strengths | 5 mg or 10 mg per vial |
| Catalog reference | SBL-9885 |
Where it fits in GH-axis research.
Mod GRF 1-29 is a tool for GHRH-receptor signalling and pulsatile growth hormone release. Researchers often pair it with the ghrelin-receptor agonist ipamorelin: the two signals act on separate pituitary receptors and reinforce each other. Its unmodified parent is sermorelin, and further down the axis sits IGF-1 LR3.
Documentation.
Available analytical documentation is organized by compound, strength and format in the COA library. Do not treat a report as lot-specific unless a documented lot match is shown.
Handling.
Until it is opened, store the vial cold and dry, shielded from light. Most labs mix it with bacteriostatic water and refrigerate the solution once it has been reconstituted.
Questions.
With DAC or without?
DAC ties the peptide to albumin so it lingers for days. Without it, the peptide clears far sooner.
Is CJC-1295 No DAC the same as Mod GRF 1-29?
Yes. They are two names for one peptide: GHRH 1-29 with four substitutions.
Why pair it with ipamorelin?
Because ipamorelin works through the ghrelin receptor and CJC-1295 through the GHRH receptor, pairing them shows how the two pathways combine.
Further reading.
CJC-1295 No DAC reconstitution calculator
CJC-1295 and ipamorelin: why researchers pair them
Sermorelin vs tesamorelin: two GHRH analogs, compared
For laboratory research use only. Not for human or veterinary use.
